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IRF5 Protein (His tag)

IRF5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7455628
  • Target See all IRF5 Proteins
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Protein Type
    Recombinant
    Origin
    • 17
    • 4
    • 1
    Human
    Source
    • 9
    • 8
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IRF5 protein is labelled with His tag.
    Purpose
    Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.
    Characteristics
    Extracellular Domain Protein
    Purification
    Affinity purification
    Purity
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IRF5 Protein
  • Restrictions
    For Research Use only
  • Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 30 % Glycerol, 1 mM DTT, pH 8.0.
    Storage
    -80 °C
    Storage Comment
    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Alternative Name
    IRF5 (IRF5 Products)
    Background
    Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.
    Molecular Weight
    57.1 KDa
    UniProt
    Q13568
    Pathways
    TLR Signaling, Autophagy
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