CCL18 Protein (His tag)

Catalog No. ABIN7455629

This Recombinant CCL18 protein is expressed in Escherichia coli (E. coli).

Quick Overview for CCL18 Protein (His tag) (ABIN7455629)

Target: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: Greater than 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This CCL18 protein is labelled with His tag.

Purpose: Recombinant Human C-C Motif Chemokine 18 is produced by our E.coli expression system and the target gene encoding Ala21-Ala89 is expressed with a 6His tag at the N-terminus.

Characteristics: Extracellular Domain Protein

Purification: Affinity purification

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Alternative Name: CCL18

Background: C-C Motif Chemokine 18,Alternative Macrophage Activation-Associated CC Chemokine 1,AMAC-1,CC Chemokine PARC,Dendritic Cell Chemokine 1,DC-CK1,Macrophage Inflammatory Protein 4,MIP-4,Pulmonary and Activation-Regulated Chemokine,Small-Inducible Cytokine A18,CCL18,AMAC1,DCCK1,MIP4,PARC,SCYA18
C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4 and CD8 T-cells and thus may play a role in both humoral and cell-mediated immunity responses.

Molecular Weight: 10.1 KDa

UniProt: P55774