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F4/80 Protein

EMR1 Origin: Human Host: HEK-293 Cells Synthetic
Catalog No. ABIN7491531
  • Target See all F4/80 (EMR1) Proteins
    F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
    Protein Type
    Synthetic
    Origin
    • 8
    • 2
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purpose
    Human ADGRE1 full length protein-synthetic nanodisc
    Characteristics
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product EMR1 Protein
  • Application Notes
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    Comment

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
    Alternative Name
    ADGRE1 (EMR1 Products)
    Synonyms
    EMR1 Protein, TM7LN3 Protein, DD7A5-7 Protein, EGF-TM7 Protein, F4/80 Protein, Gpf480 Protein, Ly71 Protein, adhesion G protein-coupled receptor E1 Protein, ADGRE1 Protein, LOC100424335 Protein, Adgre1 Protein
    Background
    EMR1, TM7LN3
    Description: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]
    Molecular Weight
    The human full length ADGRE1 protein has a MW of 97.5 kDa
    UniProt
    Q14246
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