Claudin 2 Protein (CLDN2)
Quick Overview for Claudin 2 Protein (CLDN2) (ABIN7491596)
Target
See all Claudin 2 (CLDN2) ProteinsProtein Type
Origin
Source
-
-
Purpose
- Human CLDN2 full length protein-synthetic nanodisc
-
Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $16,231.82Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $20,480.57Your project requires further customization? Contact us and discover our custom protein solutions
-
Claudin 2 (CLDN2) (AA 1-230) protein (His tag)
custom-made CLDN2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 2 (CLDN2) (AA 1-230) protein (His tag)custom-made CLDN2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 2 (CLDN2) (AA 29-80) protein (GST tag)CLDN2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Claudin 2 (CLDN2) (AA 1-230) protein (GST tag)CLDN2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Claudin 2 (CLDN2) (AA 29-78) protein (Fc Tag)CLDN2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 2 (CLDN2) protein (Myc-DYKDDDDK Tag)CLDN2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Comment
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Expiry Date
- 12 months
-
-
- Claudin 2 (CLDN2)
-
Alternative Name
- CLDN2
-
Background
- This protein belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
-
Molecular Weight
- The human full length CLDN2 protein has a MW of 24.5 kDa
-
UniProt
- P57739
-
Pathways
- Hepatitis C
Target
-
