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- Target See all CX3CR1 Proteins
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CX3CR1 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CX3CR1 Protein
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Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-355) protein (His tag)
custom-made CX3CR1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-354) protein (His tag)custom-made CX3CR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-31) protein (Fc Tag)CX3CR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-36) protein (GST tag)CX3CR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-355) protein (GST tag)CX3CR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
- Alternative Name
- CX3CR1 (CX3CR1 Products)
- Background
- Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
- Molecular Weight
- The human full length CX3CR1 protein has a MW of 40.4 kDa
- UniProt
- P49238
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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