GRPR Protein
GRPR
Origin: Human
Host: HEK-293 Cells
Synthetic
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- Target See all GRPR Proteins
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human GRPR full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GRPR Protein
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Gastrin-Releasing Peptide Receptor (GRPR) (AA 1-384) protein (GST tag)
GRPR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
- Alternative Name
- GRPR (GRPR Products)
- Synonyms
- GRPR Protein, GRP-R Protein, gastrin releasing peptide receptor Protein, GRPR Protein, Grpr Protein
- Background
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BB2, BB2R, BRS2
Description: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length GRPR protein has a MW of 43.2 kDa
- UniProt
- P30550
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