CD5 Protein (CD5) (Biotin,His-Avi Tag)
Quick Overview for CD5 Protein (CD5) (Biotin,His-Avi Tag) (ABIN7489028)
Target
See all CD5 ProteinsProtein Type
Origin
Source
Purity
Grade
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Purification tag / Conjugate
- This CD5 protein is labelled with Biotin,His-Avi Tag.
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Purpose
- Biotinylated Mouse CD5 Protein, His,Avitag™ (MALS verified)
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Sequence
- Gln 24 - Asn 370
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Characteristics
- Biotinylated Mouse CD5 Protein, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Asn 370 (Accession # P13379).
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Endotoxin Level
- 1.0 EU per μg
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Comment
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 41.4 kDa. The protein migrates as 53-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- CD5
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Alternative Name
- CD5
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Background
- T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
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Molecular Weight
- 41.4 kDa
Target
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