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CD5 Protein (CD5) (Biotin,His-Avi Tag)

This Recombinant CD5 protein is produced in HEK-293 Cells.
Catalog No. ABIN7489028

Quick Overview for CD5 Protein (CD5) (Biotin,His-Avi Tag) (ABIN7489028)

Target

See all CD5 Proteins
CD5

Protein Type

Recombinant

Origin

  • 19
  • 4
  • 4
  • 2
  • 1
Mouse

Source

  • 18
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

90 %

Grade

MALS verified
  • Purification tag / Conjugate

    This CD5 protein is labelled with Biotin,His-Avi Tag.

    Purpose

    Biotinylated Mouse CD5 Protein, His,Avitag™ (MALS verified)

    Sequence

    Gln 24 - Asn 370

    Characteristics

    Biotinylated Mouse CD5 Protein, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Asn 370 (Accession # P13379).

    Endotoxin Level

    1.0 EU per μg
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  • Comment

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 41.4 kDa. The protein migrates as 53-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    CD5

    Alternative Name

    CD5

    Background

    T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.

    Molecular Weight

    41.4 kDa
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