RSV Pre-F0 protein (FITC,His tag)

Catalog No. ABIN7488836

Recombinant RSV Pre-F0 protein expressed in HEK-293 Cells.

Quick Overview for RSV Pre-F0 protein (FITC,His tag) (ABIN7488836)

Target: RSV Pre-F0

Protein Type: Recombinant

Origin: Human respiratory syncytial virus A

Source: HEK-293 Cells

Purity: 90 %

Product Details

Purification tag / Conjugate: FITC,His tag

Purpose: FITC-Labeled Human respiratory syncytial virus A (strain A2) Pre-F0 Protein, His Tag

Sequence: Gln 26- Leu 513

Characteristics: FITC-Labeled Human respiratory syncytial virus A (strain A2) Pre-F0, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 26- Leu 513 (Accession # P03420).

Endotoxin Level: 1.0 EU per μg

Application Details

Comment:

This protein carries a polyhistidine tag at the C-terminus. (FITC ,10xHis) The protein has a calculated MW of 56.1 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C, avoid light

Target Details

Target: RSV Pre-F0

Background: Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation. Both states exhibit epitopes targeted by neutralizing antibodies, and post-fusion RSV F is being developed as a vaccine candidate.

Molecular Weight: 56.1 kDa