CXCR6 Protein-VLP
Quick Overview for CXCR6 Protein-VLP (ABIN7489101)
Target
See all CXCR6 ProteinsProtein Type
Origin
Source
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Purpose
- Human CXCR6 / CD186 Full Length Protein (VLP)
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Sequence
- Ala 2 - Leu 342
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Characteristics
- Human CXCR6 Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Leu 342 (Accession # O00574-1).
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Endotoxin Level
- 1.0 EU per μg
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Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) protein (His tag)
custom-made CXCR6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-351) protein (His tag)custom-made CXCR6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X-C Motif) Receptor 6 (CXCR6) proteinCXCR6 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) protein (GST tag)CXCR6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, Arginine, pH 7.4
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Storage
- -80 °C
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Storage Comment
- -70°C
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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Alternative Name
- CXCR6
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Background
- The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
Target
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