Hemagglutinin Protein (HA) (His tag)
Quick Overview for Hemagglutinin Protein (HA) (His tag) (ABIN7488942)
Target
See all Hemagglutinin (HA) ProteinsProtein Type
Origin
Source
Purity
Grade
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Virus Strain
- A/Darwin/6/2021
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Purification tag / Conjugate
- This Hemagglutinin protein is labelled with His tag.
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Purpose
- Influenza A [A/Darwin/6/2021 (H3N2)] Hemagglutinin (HA) Protein, His Tag (MALS verified)
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Sequence
- Gln 17 - Ile 531
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Characteristics
- Influenza A [A/Darwin/6/2021 (H3N2)] HA Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 17 - Ile 531 (Accession # EPI_ISL_3534319).
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Endotoxin Level
- 1.0 EU per μg
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Comment
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 63 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS
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Storage
- -20 °C
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Storage Comment
- -20°C
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- Hemagglutinin (HA)
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Alternative Name
- Hemagglutinin
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Target Type
- Influenza Virus
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Background
- Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
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Molecular Weight
- 63 kDa
Target
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