Mesothelin Protein (MSLN) (Fc Tag)
Quick Overview for Mesothelin Protein (MSLN) (Fc Tag) (ABIN7482581)
Target
See all Mesothelin (MSLN) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Mesothelin protein is labelled with Fc Tag.
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Purpose
- Mouse Mesothelin / MSLN Protein, Fc Tag
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Sequence
- Asp 298 - Ser 600
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Characteristics
- Mouse Mesothelin Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Asp 298 - Ser 600 (Accession # Q61468-1).
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Endotoxin Level
- 1.0 EU per μg
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Mesothelin (MSLN) (AA 296-580) protein (Fc Tag)
MSLN Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (Fc-Avi Tag,Biotin)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (Fc Tag)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Mesothelin (MSLN) (AA 296-580) protein (His-Avi Tag)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 406-690) protein (His tag)MSLN Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (mFc-His Tag)MSLN Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. WB
Mesothelin (MSLN) (AA 406-690) protein (His tag,Biotin)MSLN Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (His-Avi Tag,Biotin)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 1-375) protein (His tag)custom-made MSLN Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mesothelin (MSLN) (AA 1-375) protein (His tag)custom-made MSLN Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Comment
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This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 60.6 kDa. The protein migrates as 67-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
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Storage
- -20 °C
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Storage Comment
- -20°C
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- Mesothelin (MSLN)
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Alternative Name
- Mesothelin
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Background
- Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
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Molecular Weight
- 60.6 kDa
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Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
Target
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