Claudin 4 Protein-VLP (CLDN4) (AA 1-209)
Quick Overview for Claudin 4 Protein-VLP (CLDN4) (AA 1-209) (ABIN7504302)
Target
See all Claudin 4 (CLDN4) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-209
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Purpose
- Human Claudin 4 Protein-VLP
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Sequence
- Met1-Val209
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Characteristics
- Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Claudin 4 (CLDN4) (AA 1-210) protein (His tag)
custom-made CLDN4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 4 (CLDN4) (AA 1-209) protein (His tag)custom-made CLDN4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 4 (CLDN4) proteinCLDN4 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Claudin 4 (CLDN4) (AA 145-157) protein (Fc Tag)CLDN4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 4 (CLDN4) (AA 145-157) protein (mFc Tag)CLDN4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 4 (CLDN4) (AA 1-209) protein (GST tag)CLDN4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Supplied as 0.22μm filtered solution in PBS, 300 mM L-Arginine ( pH 7.4).
Notice: If you need it for immunization, Do Not use any adjuvant. -
Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Claudin 4 (CLDN4)
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Alternative Name
- Claudin 4
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Background
- Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
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Molecular Weight
- 23.31 kDa.
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UniProt
- O14493
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Pathways
- Hepatitis C
Target
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