CD38 Protein (AA 44-301) (His tag)
Quick Overview for CD38 Protein (AA 44-301) (His tag) (ABIN7504917)
Target
See all CD38 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 44-301
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Purification tag / Conjugate
- This CD38 protein is labelled with His tag.
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Sequence
- Leu 44-Ile 301
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Characteristics
- A DNA sequence encoding the Cynomolgus macaques CD38/ADPRC1 protein (Q5VAN0) (Leu 44-Ile 301) was expressed with N-His tag.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CD38
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Background
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Abbreviation: macaques CD38,ADPRC1
Target Synonym: ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,CD38,T10
Background: CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
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Molecular Weight
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Calculated MW: 28.27 kDa
Observed MW: 32 kDa
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UniProt
- Q5VAN0
Target
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