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CD38 Protein (AA 44-301) (His tag)

Recombinant CD38 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7504917

Quick Overview for CD38 Protein (AA 44-301) (His tag) (ABIN7504917)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 26
  • 10
  • 5
  • 2
  • 1
Cynomolgus

Source

  • 18
  • 9
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 44-301

    Purification tag / Conjugate

    This CD38 protein is labelled with His tag.

    Sequence

    Leu 44-Ile 301

    Characteristics

    A DNA sequence encoding the Cynomolgus macaques CD38/ADPRC1 protein (Q5VAN0) (Leu 44-Ile 301) was expressed with N-His tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    CD38

    Background

    Abbreviation: macaques CD38,ADPRC1

    Target Synonym: ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,CD38,T10

    Background: CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

    Molecular Weight

    Calculated MW: 28.27 kDa

    Observed MW: 32 kDa

    UniProt

    Q5VAN0
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