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CLIC5 Protein (AA 1-251) (His tag)

This Recombinant CLIC5 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7504921

Quick Overview for CLIC5 Protein (AA 1-251) (His tag) (ABIN7504921)

Target

See all CLIC5 Proteins
CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Protein Type

Recombinant

Origin

  • 7
  • 2
Human

Source

  • 4
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 1-251

    Purification tag / Conjugate

    This CLIC5 protein is labelled with His tag.

    Sequence

    Met 1-Ser251

    Characteristics

    Recombinant Human Chloride Intracellular Channel Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Ser251 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    <1.0 EU per μg of the protein as determined by the LAL method.
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    Product
    Expression System
    Conjugate
    Origin
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $13,686.36
    Expression System Cell-free protein synthesis (CFPS)
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    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

    Alternative Name

    CLIC5

    Background

    Abbreviation: CLIC5

    Target Synonym: Chloride Intracellular Channel Protein 5,CLIC5

    Background: Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specifically associates with the cytoskeleton of placenta microvilli. CLIC5 is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.

    Molecular Weight

    Calculated MW: 30.3 kDa

    Observed MW: 32 kDa

    UniProt

    Q9NZA1

    Pathways

    Sensory Perception of Sound
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