CLIC5 Protein (AA 1-251) (His tag)
Quick Overview for CLIC5 Protein (AA 1-251) (His tag) (ABIN7504921)
Target
See all CLIC5 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-251
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Purification tag / Conjugate
- This CLIC5 protein is labelled with His tag.
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Sequence
- Met 1-Ser251
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Characteristics
- Recombinant Human Chloride Intracellular Channel Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Ser251 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- <1.0 EU per μg of the protein as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CLIC5 (Chloride Intracellular Channel 5 (CLIC5))
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Alternative Name
- CLIC5
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Background
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Abbreviation: CLIC5
Target Synonym: Chloride Intracellular Channel Protein 5,CLIC5
Background: Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specifically associates with the cytoskeleton of placenta microvilli. CLIC5 is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.
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Molecular Weight
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Calculated MW: 30.3 kDa
Observed MW: 32 kDa
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UniProt
- Q9NZA1
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Pathways
- Sensory Perception of Sound
Target
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