PDCD4 Protein (AA 1-325) (His tag)
Quick Overview for PDCD4 Protein (AA 1-325) (His tag) (ABIN7504954)
Target
See all PDCD4 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-325
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Purification tag / Conjugate
- This PDCD4 protein is labelled with His tag.
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Sequence
- Met1-Asn325
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Characteristics
- A DNA sequence encoding the Human PDCD4(Q53EL6) (1M-325N) was expressed with a polyhistidine tag at the N-terminus.
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Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (His tag)
custom-made PDCD4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (His tag)custom-made PDCD4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Programmed Cell Death 4 (PDCD4) (AA 212-357) protein (His-IF2DI Tag)PDCD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (GST tag)PDCD4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Programmed Cell Death 4 (PDCD4) (AA 1-469) proteinPDCD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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used as Immunogen for (ABIN6999911, ABIN7234265, ABIN7234266 and ABIN7234267)
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- PDCD4 (Programmed Cell Death 4 (PDCD4))
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Alternative Name
- PDCD4
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Background
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Abbreviation: PDCD4
Target Synonym: Death up-regulated gene protein,Dug,H731,Ma3,MGC33046,MGC33047,Neoplastic transformation inhibitor,Neoplastic transformation inhibitor protein,Nuclear antigen H731,Nuclear antigen H731 like,Nuclear antigen H731 like protein,Nuclear antigen H731-like,PDCD 4,Pdcd4,PDCD4,Programmed cell death 4,programmed cell death 4 (neoplastic transformation inhibitor),Programmed cell death protein 4,Protein 197/15a,Protein MA-3,Tis,Topoisomerase-inhibitor suppressed protein
Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation.
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Molecular Weight
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Calculated MW: 36.9 kDa
Observed MW: 41-43 kDa
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UniProt
- Q53EL6
Target
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