PDCD4 Protein (AA 1-325) (His tag)
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- Target See all PDCD4 Proteins
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-325
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PDCD4 protein is labelled with His tag.
- Sequence
- Met1-Asn325
- Characteristics
- A DNA sequence encoding the Human PDCD4(Q53EL6) (1M-325N) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PDCD4 Protein
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Programmed Cell Death 4 (PDCD4) (AA 212-357) protein (His tag)
PDCD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (GST tag)PDCD4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (Strep Tag)Crystallography grade PDCD4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (Strep Tag)Crystallography grade PDCD4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Comment
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used as Immunogen for (ABIN6999911, ABIN7234265, ABIN7234266 and ABIN7234267)
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Alternative Name
- PDCD4 (PDCD4 Products)
- Synonyms
- H731 Protein, D19Ucla1 Protein, Ma3 Protein, Tis Protein, Dug Protein, cb45 Protein, pdcd4 Protein, sb:cb45 Protein, wu:fc84b08 Protein, h731 Protein, MGC69337 Protein, PDCD4 Protein, wu:fa55g03 Protein, wu:fb08a11 Protein, wu:fe01a02 Protein, zgc:66311 Protein, programmed cell death 4 Protein, programmed cell death 4b Protein, programmed cell death 4 L homeolog Protein, programmed cell death 4 (neoplastic transformation inhibitor) Protein, programmed cell death 4a Protein, PDCD4 Protein, Pdcd4 Protein, pdcd4b Protein, pdcd4.L Protein, pdcd4 Protein, pdcd4a Protein
- Background
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Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation.
Synonym: Death up-regulated gene protein,Dug,H731,Ma3,MGC33046,MGC33047,Neoplastic transformation inhibitor,Neoplastic transformation inhibitor protein,Nuclear antigen H731,Nuclear antigen H731 like,Nuclear antigen H731 like protein,Nuclear antigen H731-like,PDCD 4,Pdcd4,PDCD4,Programmed cell death 4,programmed cell death 4 (neoplastic transformation inhibitor),Programmed cell death protein 4,Protein 197/15a,Protein MA-3,Tis,Topoisomerase-inhibitor suppressed protein
- Molecular Weight
- 36.9 kDa
- UniProt
- Q53EL6
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