CTNNB1 Protein (AA 131-670)
Quick Overview for CTNNB1 Protein (AA 131-670) (ABIN7504998)
Target
See all CTNNB1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 131-670
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Sequence
- Met131-Tyr670
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Characteristics
- A DNA sequence encoding the Human Human CTNNB1 Protein(P35222)(131-670)was expressed with a polyhistidine tag at the N-terminus.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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Alternative Name
- CTNNB1
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Background
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Abbreviation: CTNNB1
Target Synonym: Catenin beta-1,Beta-catenin,CTNNB,OK,SW-cl.35,PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.
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Molecular Weight
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Calculated MW: 59 kDa
Observed MW: 59 kDa
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UniProt
- P35222
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Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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