Desmin Protein (DES) (AA 2-470) (His tag)
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- Target See all Desmin (DES) Proteins
- Desmin (DES)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-470
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Desmin protein is labelled with His tag.
- Sequence
- Ser 2-Leu 470
- Characteristics
- A DNA sequence encoding the Human DES protein (P17661) (Ser 2-Leu 470) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product DES Protein
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Desmin (DES) (AA 1-470) protein (His tag)
custom-made DES Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Desmin (DES) (AA 1-469) protein (His tag)custom-made DES Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Desmin (DES) (AA 142-467) protein (His tag)DES Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Desmin (DES) (AA 361-470) protein (GST tag)DES Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Desmin (DES)
- Alternative Name
- DES (DES Products)
- Background
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Abbreviation: DES
Target Synonym: Desmin,DES,desmin
Background: Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
- Molecular Weight
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Calculated MW: 51.48 kDa
Observed MW: 58 kDa
- UniProt
- P17661
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