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Desmin Protein (DES) (His tag)

DES Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318402
  • Target See all Desmin (DES) Proteins
    Desmin (DES)
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 7
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Desmin protein is labelled with His tag.
    Purpose
    Recombinant Human Desmin Protein (His Tag)
    Sequence
    Val260-Leu470
    Characteristics
    Recombinant Human Desmin is produced by our E.coli expression system and the target gene encoding Val260-Leu470 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DES Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Desmin (DES)
    Alternative Name
    Desmin (DES Products)
    Synonyms
    DES Protein, des-b Protein, MGC80853 Protein, des Protein, csm1 Protein, csm2 Protein, desm Protein, cmd1i Protein, MGC75911 Protein, LOC100220724 Protein, desmin Protein, cb290 Protein, fb59a12 Protein, wu:fb59a12 Protein, zgc:109859 Protein, CSM1 Protein, CSM2 Protein, LGMD2R Protein, wu:fc11d08 Protein, zgc:154009 Protein, des-a Protein, MGC52614 Protein, desmin Protein, desmin, gene 1 L homeolog Protein, desmin, gene 1 Protein, desmin a Protein, desmin b Protein, desmin, gene 1 S homeolog Protein, desmin, gene 2 S homeolog Protein, DES Protein, des.1.L Protein, des.1 Protein, des Protein, desma Protein, Des Protein, desmb Protein, des.1.S Protein, des.2.S Protein
    Background

    Background: Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.

    Synonym: Desmin, DES

    Molecular Weight
    26.7 kDa
    UniProt
    P17661
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