TIMP3 Protein (AA 24-144) (His tag)

Catalog No. ABIN7505147

This Recombinant TIMP3 protein is expressed in Escherichia coli (E. coli).

Quick Overview for TIMP3 Protein (AA 24-144) (His tag) (ABIN7505147)

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 24-144

Purification tag / Conjugate: This TIMP3 protein is labelled with His tag.

Sequence: Cys 24-Asn 144

Characteristics: A DNA sequence encoding the Human TIMP3 protein (P35625) (Cys 24-Asn 144) was expressed with a N-10His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Alternative Name: TIMP3

Background:

Abbreviation: TIMP3

Target Synonym: HSMRK222,K222TA2,Metalloproteinase inhibitor 3,MIG 5 protein,SFD,TIMP 3,TIMP-3,Tissue Inhibitor of Metalloproteinase 3

Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

Molecular Weight:

Calculated MW: 13.2 kDa

Observed MW: 15 kDa

UniProt: P35625