PIK3R5 Protein (AA 1-494) (His tag)
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- Target See all PIK3R5 Proteins
- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-494
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PIK3R5 protein is labelled with His tag.
- Sequence
- Met 1-Pro 494
- Characteristics
- A DNA sequence encoding the Human PIK3R5 protein (Q8WYR1-2) (Met 1-Pro 494) was expressed with a C-His,N-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PIK3R5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
- Alternative Name
- PIK3R5 (PIK3R5 Products)
- Background
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Abbreviation: PIK3R5
Target Synonym: Phosphoinositide 3-kinase regulatory subunit 5, PIK3R5,PI3-kinase regulatory subunit 5
Background: Phosphoinositide 3-kinase regulatory subunit 5 (PIK3R5, also PI3-kinase p101 subunit, Ptdlns-3-kinase p101, and p101-PI3K) is a 97 kDa regulatory subunit of the PI3K gamma complex. It is expressed as a heterodimer with the catalytic subunit PIK3CG/p120. Human PIK3R5 is 880 amino acids (aa) in length. The heterodimerization region is made up of aa 25-101, and aa 653-753 comprise the region for interaction with G beta gamma proteins. A second 55 kDa isoform is formed by the deletion of aa 1-386.
- Molecular Weight
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Calculated MW: 54.23 kDa
Observed MW: 58 kDa
- UniProt
- Q8WYR1-2
- Pathways
- PI3K-Akt Signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
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