PGD Protein (AA 1-483) (His tag)

Catalog No. ABIN7505267

Product Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Protein Type: Recombinant

Protein Characteristics: AA 1-483

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PGD protein is labelled with His tag.

Sequence: Met 1-Ala 483

Characteristics: A DNA sequence encoding the Human PGD protein (P52209) (Met 1-Ala 483) was expressed with a N-His&C-His.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: PGD (PGD Products)

Background:

Abbreviation: PGD

Target Synonym: 6-phosphogluconate dehydrogenase,Decarboxylating,PGD,PGDH,6PGD

Background: 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.

Molecular Weight:

Calculated MW: 53.02 kDa

Observed MW: 55 kDa

UniProt: P52209