CD38 Protein (AA 45-304) (His tag)

Catalog No. ABIN7505424

Product Details

Target: CD38

Protein Type: Recombinant

Protein Characteristics: AA 45-304

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CD38 protein is labelled with His tag.

Sequence: Leu 45-Thr 304

Characteristics: A DNA sequence encoding the Mouse CD38/ADPRC1 protein (P56528) (Leu 45-Thr 304) was expressed with N-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CD38

Abstract: CD38 Products

Background:

Abbreviation: CD38,ADPRC1

Target Synonym: cADPr hydrolase 1,CD38 antigen (p45),CD38 antigen,CD38 Molecule,CD38,Cyclic ADP-ribose hydrolase 1,Cyclic ADP-ribose Hydrolase,EC 3.2.2.5,NAD(+) nucleosidase,T10,ADPRC 1-rs1,ADPRC1,Cd38,Cd38-rs1,I-19

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

Molecular Weight:

Calculated MW: 28.49 kDa

Observed MW: 32 kDa

UniProt: P56528