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MUC16 Protein (AA 6188-6372) (His tag)

This Recombinant MUC16 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7505452

Quick Overview for MUC16 Protein (AA 6188-6372) (His tag) (ABIN7505452)

Target

See all MUC16 (CA125) Proteins
MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Protein Type

Recombinant

Origin

  • 17
  • 3
  • 2
  • 2
Mouse

Source

  • 13
  • 4
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 6188-6372

    Purification tag / Conjugate

    This MUC16 protein is labelled with His tag.

    Sequence

    Ile 6188-Ser 6372

    Characteristics

    A DNA sequence encoding the Mouse MUC16 protein (A0A140LJ72) (Ile 6188-Ser 6372) was expressed with N-His tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

    Alternative Name

    MUC16

    Background

    Abbreviation: MUC16

    Target Synonym: Mucin 16,Muc16

    Background: Mucin-16 is a heavily O-glycosylated protein that can be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus, which induces proteolytic cleavage and liberation of extracellular domain. I provides protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Mucin-16 is composed of three domains: a Serine, Threonine-rich N-terminal domain, a repeated domain containing between 12 and 60 partially conserved tandem repeats of 156 amino acids and a C-terminal transmembrane domain with a short cytoplasmic tail.

    Molecular Weight

    Calculated MW: 20.24 kDa

    Observed MW: 25 kDa

    UniProt

    A0A140LJ72
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