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MUC16 Protein (His tag,AVI tag)

CA125 Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
Catalog No. ABIN7520340
  • Target See all MUC16 (CA125) Proteins
    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 15
    • 4
    • 2
    • 2
    Human
    Source
    • 14
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MUC16 protein is labelled with His tag,AVI tag.
    Purpose
    Active Recombinant Human MUC-16/CA125 Protein
    Sequence
    GFTHWIPVPT SSTPGTSTVD LGSGTPSSLP SPTTAGPLLV PFTLNFTITN LKYEEDMHCP GSRKFNTTER VLQSLLGPMF KNTSVGPLYS GCRLTLLRSE KDGAATGVDA ICTHRLDPKS PGVDREQLYW ELSQLTNGIK ELGPYTLDRN SLYVNGFTHQ TSAPNTSTPG TSTVDLGTSG TPSSLPSPTS AGPLLVPFTL NFTITNLQYE EDMHHPGSRK FNTTERVLQG LLGPMFKNTS VGLLYSGCRL TLLRPEKNGA ATGM
    Specificity
    Gly12660-Met12923
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Loaded Human Mesothelin/MSLN Protein, C-hFc&His on ProA Biosensor, can bind Human CA125 Protein, C-His&Avi with an affinity constant of 17.2 nM as determined in BLI assay (Gator).
    Top Product
    Discover our top product CA125 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
    Alternative Name
    MUC-16/CA125 (CA125 Products)
    Synonyms
    CA125 Protein, 1110008I14Rik Protein, Ca125 Protein, Gm1480 Protein, RGD1308422 Protein, MUC16 Protein, mucin 16, cell surface associated Protein, mucin 16 Protein, mucin-16 Protein, MUC16 Protein, Muc16 Protein, LOC476718 Protein, LOC712735 Protein
    Background

    Description: The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 Molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

    Name: CA125,MUC16,mucin-16

    Gene ID
    94025
    UniProt
    Q8WXI7
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