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Clusterin Protein (CLU) (AA 22-226) (His tag)

Recombinant Clusterin protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7505529

Quick Overview for Clusterin Protein (CLU) (AA 22-226) (His tag) (ABIN7505529)

Target

See all Clusterin (CLU) Proteins
Clusterin (CLU)

Protein Type

Recombinant

Origin

  • 17
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Rat

Source

  • 20
  • 8
  • 7
  • 3
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 22-226

    Purification tag / Conjugate

    This Clusterin protein is labelled with His tag.

    Sequence

    Glu 22-Arg 226

    Characteristics

    A DNA sequence encoding the Rat Clusterin/ApoJ protein (P05371 ) (Glu 22-Arg 226) was expressed with N-His tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    Clusterin (CLU)

    Alternative Name

    Clusterin

    Background

    Abbreviation: Clusterin,ApoJ

    Target Synonym: Clusterin,Aging-Associated Gene 4 Protein,Apolipoprotein J,Apo-J,Complement Cytolysis Inhibitor,CLI,Complement-Associated Protein SP-40,Ku70-Binding Protein 1,NA1/NA2,Testosterone-Repressed Prostate Message 2,TRPM-2,CLU,APOJ,CLI,KUB1,AAG4,AP

    Background: Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.

    Molecular Weight

    Calculated MW: 22.44 kDa

    Observed MW: 28 kDa

    UniProt

    P05371

    Pathways

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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