MCAM Protein (AA 151-350) (His tag)

Catalog No. ABIN7505548

This Recombinant MCAM protein is produced in Escherichia coli (E. coli).

Quick Overview for MCAM Protein (AA 151-350) (His tag) (ABIN7505548)

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Protein Type: Recombinant

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 151-350

Purification tag / Conjugate: This MCAM protein is labelled with His tag.

Sequence: His 151-Val 350

Characteristics: A DNA sequence encoding the Rat CD146/MCAM protein (Q9EPF2) (His 151-Val 350) was expressed with N-His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Alternative Name: CD146

Background:

Abbreviation: CD146,MCAM

Target Synonym: Cell surface glycoprotein MUC18,MUC18,Mcam,Gicerin,Melanoma cell adhesion molecule,Melanoma-associated antigen MUC18,CD146

Background: Melanomia Cell Adhesion Molecule (MCAM), also known as CD146 and MUC18, is a putative Ig-superfamily adhesion molecule that is expressed on endothelial cells and a variety of tumor cells. MCAM is associated with tumor progression and metastasis and may be involved in embryonic neural development. An alternately spliced isoform of rat MCAM has a 40 residue deletion in the cytoplasmic domain.

Molecular Weight:

Calculated MW: 21.89 kDa

Observed MW: 30 kDa

UniProt: Q9EPF2