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CD5L Protein (AA 1-347) (His tag)

CD5L Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505645
  • Target See all CD5L Proteins
    CD5L (CD5 Molecule-Like (CD5L))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-347
    Origin
    • 7
    • 4
    • 2
    Human
    Source
    • 7
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD5L protein is labelled with His tag.
    Sequence
    Met1-Gly347
    Characteristics
    A DNA sequence encoding the Human CD5L protein (O43866) (Met1-Gly347) was expressed with a C-His.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    CD5L (CD5 Molecule-Like (CD5L))
    Alternative Name
    CD5L (CD5L Products)
    Background

    Abbreviation: CD5L,hAIM

    Target Synonym: CD5 antigen-like,Apoptosis inhibitor expressed by macrophages,hAIM,CT-2,IgM-associated peptide,SP-alpha,CD5L,API6,UNQ203/PRO229

    Background: CD5 Antigen-Like (CD5L) is a soluble protein that belongs to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. CD5L is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues. It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram-negative bacteria and the SRCR domain one of CD5L retains both the LPS and LTA binding activities. Furthermore, CD5L seems to play a role as an inhibitor of apoptosis.

    Molecular Weight

    Calculated MW: 38.06 kDa

    Observed MW: 42 kDa

    UniProt
    O43866
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