CD5L Protein (AA 22-352) (His tag)

Catalog No. ABIN7274205

Product Details

Target: CD5L (CD5 Molecule-Like (CD5L))

Protein Type: Recombinant

Protein Characteristics: AA 22-352

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This CD5L protein is labelled with His tag.

Purpose: Mouse CD5L Protein

Sequence: Glu22-Val352

Characteristics: Recombinant Mouse CD5L Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Val352.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CD5L (CD5 Molecule-Like (CD5L))

Alternative Name: CD5L (CD5L Products)

Synonyms: AIM Protein, API6 Protein, PRO229 Protein, SP-ALPHA Protein, Spalpha Protein, 1/6 Protein, AAC-11 Protein, AI047839 Protein, Api6 Protein, CT2 Protein, Pdp Protein, Sp-alpha Protein, CD5L Protein, CD5 molecule like Protein, CD5 antigen-like Protein, Cd5 molecule-like Protein, CD5 molecule-like Protein, scavenger receptor cysteine-rich domain superfamily protein-like Protein, CD5L Protein, Cd5l Protein, LOC100375137 Protein

Background: CD5L, a soluble protein belonging to the SRCR superfamily, is expressed mostly by macrophages in lymphoid and inflamed tissues. The expression of this protein is transcriptionally controlled by LXRs, members of the nuclear receptor family that play major roles in lipid homeostasis. Research undertaken over the last decade has uncovered critical roles of CD5L as a PRR of bacterial and fungal components and in the control of key mechanisms in inflammatory responses, with involvement in processes, such as infection, atherosclerosis, and cancer.

Molecular Weight: 37.7 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.

UniProt: Q9QWK4