NCR3 Protein (AA 1-135) (His tag)
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- Target See all NCR3 Proteins
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-135
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCR3 protein is labelled with His tag.
- Sequence
- Met1-Gly135
- Characteristics
- A DNA sequence encoding the Human NKp30/NCR3 protein (O14931) (Met1-Gly135) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Discover our top product NCR3 Protein
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Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (Fc Tag)
NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (His-Avi Tag)NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (His-Avi Tag,Biotin)NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (Fc Tag)NCR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (His-DYKDDDDK-Strep II Tag)NCR3 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 1-201) protein (GST tag)NCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Alternative Name
- NKp30 (NCR3 Products)
- Background
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Abbreviation: NKp30,NCR3
Target Synonym: Natural Cytotoxicity Triggering Receptor 3,Activating Natural Killer Receptor p30,Natural Killer Cell p30-Related Protein,NK-p30,NKp30,CD337,NCR3,1C7,LY117,1C7,DAAP-90L16.3,MALS
Background: Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity, and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.
- Molecular Weight
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Calculated MW: 14.74 kDa
Observed MW: 25 kDa
- UniProt
- O14931
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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