Coagulation Factor IX Protein (F9) (AA 1-471) (His tag)

Catalog No. ABIN7505722

This Recombinant Coagulation Factor IX protein is produced in HEK-293 Cells.

Quick Overview for Coagulation Factor IX Protein (F9) (AA 1-471) (His tag) (ABIN7505722)

Target: Coagulation Factor IX (F9)

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-471

Purification tag / Conjugate: This Coagulation Factor IX protein is labelled with His tag.

Sequence: Met 1-Thr 471

Characteristics: A DNA sequence encoding the full length of mouse F9 (P16294) (Met 1-Thr 471) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.

Endotoxin Level: <1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Coagulation Factor IX (F9)

Alternative Name: Coagulation Factor IX

Background:

Abbreviation: Coagulation Factor IX,F9

Target Synonym: AW111646,Cf-9,Cf9

Background: Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.

Molecular Weight:

Calculated MW: 51.3 kDa

Observed MW: 60-80 kDa

UniProt: P16294