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DKK3 Protein (AA 1-349) (His tag)

This Recombinant DKK3 protein is produced in HEK-293 Cells.
Catalog No. ABIN7505749

Quick Overview for DKK3 Protein (AA 1-349) (His tag) (ABIN7505749)

Target

DKK3

Protein Type

Recombinant

Origin

  • 14
  • 3
  • 1
  • 1
Mouse

Source

  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 1-349

    Purification tag / Conjugate

    This DKK3 protein is labelled with His tag.

    Sequence

    Met1-Ile349

    Characteristics

    A DNA sequence encoding the Mouse DKK3 protein (Q9QUN9) (Met1-Ile349) was expressed with a C-His.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    DKK3

    Background

    Abbreviation: DKK3

    Target Synonym: AW061014,C87148

    Background: DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

    Molecular Weight

    Calculated MW: 38.28 kDa

    Observed MW: 60 kDa

    UniProt

    Q9QUN9
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