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IL-4 Protein (AA 1-147)

This Recombinant IL-4 protein is produced in HEK-293 Cells.
Catalog No. ABIN7505770

Quick Overview for IL-4 Protein (AA 1-147) (ABIN7505770)

Target

See all IL-4 (IL4) Proteins
IL-4 (IL4) (Interleukin 4 (IL4))

Protein Type

Recombinant

Origin

  • 40
  • 26
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Rat

Source

  • 54
  • 20
  • 16
  • 12
  • 5
  • 4
  • 2
HEK-293 Cells

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 1-147

    Sequence

    Met1-Ser147

    Characteristics

    A DNA sequence encoding the Rat IL4 protein (P20096) (1-147) was expressed with a polyhistidine tag at the C-terminus.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    IL-4 (IL4) (Interleukin 4 (IL4))

    Alternative Name

    IL-4

    Background

    Abbreviation: IL-4

    Target Synonym: Interleukin-4,IL4,B-cell stimulatory factor 1,BSF-1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra

    Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

    Molecular Weight

    Calculated MW: 16.5 kDa

    Observed MW: 17 kDa

    UniProt

    P20096

    Pathways

    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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