MMP2 Protein (AA 1-662) (His tag)
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- Target See all MMP2 Proteins
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-662
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MMP2 protein is labelled with His tag.
- Sequence
- Met1-Cys662
- Characteristics
- A DNA sequence encoding the Rat Mmp2 protein (P33436) (Met1-Cys662) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MMP2 Protein
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Matrix Metalloproteinase 2 (MMP2) (Active) protein
MMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Matrix Metalloproteinase 2 (MMP2) (AA 34-660) protein (His tag)MMP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Matrix Metalloproteinase 2 (MMP2) (AA 424-660) protein (His-IF2DI Tag)MMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Matrix Metalloproteinase 2 (MMP2) (AA 1-660) protein (GST tag)MMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Matrix Metalloproteinase 2 (MMP2) (AA 109-660) protein (His tag)MMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Matrix Metalloproteinase 2 (MMP2) (AA 30-660) protein (His tag)MMP2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Alternative Name
- MMP2 (MMP2 Products)
- Background
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Abbreviation: MMP2
Target Synonym: 72 kDa type IV collagenase,EC 3.4.24.24,72 kDa gelatinase,Gelatinase A,Matrix metalloproteinase-2,MMP-2
Background: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrin alpha-v/beta3 on the surface of blood vessels.
- Molecular Weight
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Calculated MW: 72.71 kDa
Observed MW: 72 kDa
- UniProt
- P33436
- Pathways
- Activation of Innate immune Response
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