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MMP2 Protein (AA 34-660) (His tag)

MMP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275268
  • Target See all MMP2 Proteins
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 34-660
    Origin
    • 20
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Human
    Source
    • 23
    • 7
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MMP2 protein is labelled with His tag.
    Purpose
    Human MMP-2 Protein (pro form)
    Sequence
    Ile34-Cys660
    Characteristics
    Recombinant Human MMP-2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile34-Cys660.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product MMP2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 25 mM Tris, 150 mM NaCl, 50 % Glycerol ( pH 7.5).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Alternative Name
    MMP-2 (MMP2 Products)
    Synonyms
    2-MMP Protein, CG1794 Protein, DM2-MMP Protein, Dm2-MMP Protein, Dmel\\CG1794 Protein, MMP2 Protein, anon-WO0118547.84 Protein, dm-2MMP Protein, dmmp2 Protein, l(2)02353 Protein, mmp2 Protein, wu:fa99h12 Protein, wu:fk89d01 Protein, fgmmp-2 Protein, Mmp-2 Protein, LOC100135793 Protein, Clg4a Protein, GelA Protein, MMP-2 Protein, CLG4 Protein, CLG4A Protein, MMP-II Protein, MONA Protein, TBE-1 Protein, matrix metallopeptidase 2 Protein, Matrix metalloproteinase 2 Protein, matrix metalloproteinase 2 Protein, matrix metalloproteinase-2 Protein, MMP2 Protein, Mmp2 Protein, mmp2 Protein, LOC657982 Protein, LOC100135793 Protein
    Background
    Matrix metalloproteinase (MMP)-2 cleaves a broad spectrum of substrates, including extracellular matrix components (responsible for normal tissue remodeling) and cytokines (modulators of the inflammatory response to physiological insults such as tissue damage). MMP-2 expression is elevated in many cardiovascular pathologies (e.g., myocardial infarction, hypertensive heart disease) where tissue remodeling and inflammatory responses are perturbed.
    Molecular Weight
    71.6 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.
    UniProt
    P08253
    Pathways
    Activation of Innate immune Response
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