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CD200 Protein (CD200) (His tag)

This Recombinant CD200 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7534041

Quick Overview for CD200 Protein (CD200) (His tag) (ABIN7534041)

Target

See all CD200 Proteins
CD200

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 10
  • 2
  • 1
Human

Source

  • 14
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % by SDS-PAGE.
  • Purification tag / Conjugate

    This CD200 protein is labelled with His tag.

    Purpose

    Active Recombinant Human OX-2/CD200 Protein

    Sequence

    QVQVVTQDER EQLYTPASLK CSLQNAQEAL IVTWQKKKAV SPENMVTFSE NHGVVIQPAY KDKINITQLG LQNSTITFWN ITLEDEGCYM CLFNTFGFGK ISGTACLTVY VQPIVSLHYK FSEDHLNITC SATARPAPMV FWKVPRSGIE NSTVTLSHPN GTTSVTSILH IKDPKNQVGK EVICQVLHLG TVTDFKQTVN KG

    Specificity

    Gln31-Gly232

    Sterility

    0.22 μm filtered

    Endotoxin Level

    < 0.1 EU/μg of the protein by LAL method.

    Biological Activity Comment

    Measured by its binding ability in a functional ELISA. Immobilized Human CD200 at 2 μg/mL (100 μL/well) can bind Human CD200R with a linear range of 0.058-8.34 ng/mL.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    Buffer

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target

    CD200

    Alternative Name

    OX-2/CD200

    Background

    Description: The protein is a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Name: CD200,MOX1,MOX2,MRC,OX-2

    Gene ID

    4345

    UniProt

    P41217
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