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CD48 Protein (CD48) (Fc Tag)

This Recombinant CD48 protein is produced in HEK-293 Cells.
Catalog No. ABIN7536139

Quick Overview for CD48 Protein (CD48) (Fc Tag) (ABIN7536139)

Target

See all CD48 Proteins
CD48

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 18
  • 7
  • 3
Mouse

Source

  • 13
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % by SDS-PAGE.
  • Purification tag / Conjugate

    This CD48 protein is labelled with Fc Tag.

    Purpose

    Active Recombinant Mouse SLAMF2/CD48 Protein

    Sequence

    FQGHSIPDIN ATTGSNVTLK IHKDPLGPYK RITWLHTKNQ KILEYNYNST KTIFESEFKG RVYLEENNGA LHISNVRKED KGTYYMRVLR ETENELKITL EVFDPVPKPS IEINKTEAST DSCHLRLSCE VKDQHVDYTW YESSGPFPKK SPGYVLDLIV TPQNKSTFYT CQVSNPVSSK NDTVYFTLPC DLAR

    Specificity

    Phe23-Arg216

    Sterility

    0.22 μm filtered

    Endotoxin Level

    <0.1EU/μg

    Biological Activity Comment

    Measured by its binding ability in a functional ELISA. Immobilized Human CD48 at 10 μg/mL (100 μL/well) can bind Human CD224 with a linear range of 0.87-18.4 ng/mL.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    Buffer

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target

    CD48

    Alternative Name

    SLAMF2/CD48

    Background

    Description: This protein is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

    Name: BCM1,BLAST,BLAST1,hCD48,mCD48,MEM-102,SLAMF2,CD48

    Gene ID

    12506

    UniProt

    P18181
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