IL-3 Protein (His tag)

Catalog No. ABIN7520203

This Recombinant IL-3 protein is produced in HEK-293 Cells.

Quick Overview for IL-3 Protein (His tag) (ABIN7520203)

Target: IL-3 (Interleukin 3 (IL-3))

Protein Type: Recombinant

Origin: Rat

Source: HEK-293 Cells

Purity: > 97 % by SDS-PAGE.

Product Details

Purification tag / Conjugate: This IL-3 protein is labelled with His tag.

Purpose: Recombinant Rat IL-3 Protein

Sequence: ISDRGSDAHH LLRTLDCRTI ALEILVKLPY PQVSGLNNSD DKANLRNSTL RRVNLDEFLK SQEEFDSQDT TDIKSKLQKL KCCIPAAASD SVLPGVYNKD LDDFKKKLRF YVIHLKDLQP VSVSRPPQPT SSSDNFRPMT VEC

Specificity: Ile27-Cys169

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1EU/μg

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.4 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: IL-3 (Interleukin 3 (IL-3))

Alternative Name: IL-3

Background:

Description: IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Name: IL-3,IL3

Gene ID: 24495

UniProt: P97688

Pathways: JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy