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JAM3 Protein (Ala149Pro) (Fc Tag,His tag)

This Recombinant JAM3 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7534135
$445.50
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Quick Overview for JAM3 Protein (Ala149Pro) (Fc Tag,His tag) (ABIN7534135)

Target

See all JAM3 Proteins
JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Protein Type

Recombinant

Origin

  • 7
  • 3
Human

Source

  • 5
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % by SDS-PAGE.
  • Protein Characteristics

    Ala149Pro

    Purification tag / Conjugate

    This JAM3 protein is labelled with Fc Tag,His tag.

    Purpose

    Recombinant Human JAM-3(A149P) Protein

    Sequence

    VNLKSSNRTP VVQEFESVEL SCIITDSQTS DPRIEWKKIQ DEQTTYVFFD NKIQGDLAGR AEILGKTSLK IWNVTRRDSA LYRCEVVARN DRKEIDEIVI ELTVQVKPVT PVCRVPKPVP VGKMATLHCQ ESEGHPRPHY SWYRNDVPLP TDSRANPRFR NSSFHLNSET GTLVFTAVHK DDSGQYYCIA SNDAGSARCE EQEMEVYDLN

    Specificity

    Val32-Asn241(A149P)

    Sterility

    0.22 μm filtered

    Endotoxin Level

    < 0.1 EU/μg of the protein by LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    Buffer

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target

    JAM3 (Junctional Adhesion Molecule 3 (JAM3))

    Alternative Name

    JAM-3

    Background

    Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

    Name: JAM3,JAM-2,JAM-3,JAM-C,JAMC

    Gene ID

    83700

    UniProt

    Q9BX67
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