LI Cadherin Protein (His tag)

Catalog No. ABIN7533976

This Recombinant LI Cadherin protein is produced in HEK-293 Cells.

Quick Overview for LI Cadherin Protein (His tag) (ABIN7533976)

Target: LI Cadherin

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % by SDS-PAGE.

Product Details

Purification tag / Conjugate: This LI Cadherin protein is labelled with His tag.

Purpose: Active Recombinant Human CDH17/LI-cadherin Protein

Sequence: QEGKFSGPLK PMTFSIYEGQ EPSQIIFQFK ANPPAVTFEL TGETDNIFVI EREGLLYYNR ALDRETRSTH NLQVAALDAN GIIVEGPVPI TIKVKDINDN RPTFLQSKYE GSVRQNSRPG KPFLYVNATD LDDPATPNGQ LYYQIVIQLP MINNVMYFQI NNKTGAISLT REGSQELNPA KNPSYNLVIS VKDMGGQSEN SFSDTTSVDI IVTENIWKAP KPVEMVENST DPHPIKITQV RWNDPGAQYS LVDKEKLPRF PFSIDQEGDI YVTQPLDREE KDAYVFYAVA KDEYGKPLSY PLEIHVKVKD INDNPPTCPS PVTVFEVQEN ERLGNSIGTL TAHDRDEENT ANSFLNYRIV EQTPKLPMDG LFLIQTYAGM LQLAKQSLKK QDTPQYNLTI EVSDKDFKTL CFVQINVIDI NDQIPIFEKS DYGNLTLAED TNIGSTILTI QATDADEPFT GSSKILYHII KGDSEGRLGV DTDPHTNTGY VIIKKPLDFE TAAVSNIVFK AENPEPLVFG VKYNASSFAK FTLIVTDVNE APQFSQHVFQ AKVSEDVAIG TKVGNVTAKD PEGLDISYSL RGDTRGWLKI DHVTGEIFSV APLDREAGSP YRVQVVATEV GGSSLSSVSE FHLILMDVND NPPRLAKDYT GLFFCHPLSA PGSLIFEATD DDQHLFRGPH FTFSLGSGSL QNDWEVSKIN GTHARLSTRH TEFEEREYVV LIRINDGGRP PLEGIVSLPV TFCSCVEGSC FRPAGHQTGI PTVGM

Specificity: Gln23-Met787

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 1μg/mL (100 μL/well) can bind anti Human CDH17 antibody with a linear range of 0.01-20ng/mL.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Target Details

Target: LI Cadherin

Alternative Name: CDH17/LI-cadherin

Background:

Description: This protein is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Name: CDH16, HPT-1, HPT1,CDH17,HPT-1,HPT1

Gene ID: 1015

UniProt: Q12864