PDGF-AA Homodimer Protein

Catalog No. ABIN7536482

Recombinant protein expressed in Yeast (Pichia pastoris).

Quick Overview for PDGF-AA Homodimer Protein (ABIN7536482)

Target: PDGF-AA Homodimer

Protein Type: Recombinant

Origin: Human

Source: Yeast (Pichia pastoris)

Product Details

Purpose: Recombinant Human PDGF-AA Protein

Sequence: SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT

Specificity: Ser87-Thr211

Sterility: 0.22 μm filtered

Endotoxin Level: 600.1EU/μg

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.17 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: PDGF-AA Homodimer

Alternative Name: PDGF-AA

Background:

Description: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.

Name: PDGF1, PDGF-A

Gene ID: 5154

UniProt: P04085