GIPR Protein (AA 19-134) (Fc Tag)

Catalog No. ABIN7852638

Recombinant GIPR protein expressed in Mammalian Cells.

Quick Overview for GIPR Protein (AA 19-134) (Fc Tag) (ABIN7852638)

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Protein Type: Recombinant

Origin: Mouse

Source: Mammalian Cells

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 19-134

Purification tag / Conjugate: This GIPR protein is labelled with Fc Tag.

Purpose: Recombinant mouse GIPR protein with C-terminal human Fc tag

Specificity: Mouse GIPR (Glu19-Gln134) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Alternative Name: GIPR

Background: Predicted to enable G protein-coupled peptide receptor activity, gastric inhibitory peptide receptor activity, and glucagon family peptide binding activity. Acts upstream of or within endocrine pancreas development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in foregut-midgut junction, pancreas, and pancreas primordium. Human ortholog(s) of this gene implicated in cardiovascular system disease, diabetes mellitus, obesity, and type 2 diabetes mellitus. Orthologous to human GIPR (gastric inhibitory polypeptide receptor). [provided by Alliance of Genome Resources, Apr 2022]

Molecular Weight: predicted molecular mass of 39.5 kDa after removal of the signal peptide. The apparent molecular mass of mGIPR-hFc is 35-55 kDa due to glycosylation.

UniProt: Q0P543

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling