HIST1H1C Protein (Fc Tag)

Catalog No. ABIN7852418

This Recombinant HIST1H1C protein is expressed in Mammalian Cells.

Quick Overview for HIST1H1C Protein (Fc Tag) (ABIN7852418)

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Protein Type: Recombinant

Origin: Mouse

Source: Mammalian Cells

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Purification tag / Conjugate: This HIST1H1C protein is labelled with Fc Tag.

Purpose: Recombinant mouse HistoneH1.2 protein with N-terminal human Fc tag

Specificity: HFc (Glu99-Ala330) Mouse HistoneH1.2 (Lys34-Thr99)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Alternative Name: HistoneH1.2

Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Feb 2014]

Molecular Weight: predicted molecular mass of 32.9 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mHistoneH1.2 is 25-55 kDa due to glycosylation.

UniProt: P15864