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PRLHR Protein

This Synthetic Nanodisc PRLHR protein is produced in Mammalian Cells.
Catalog No. ABIN7538486

Quick Overview for PRLHR Protein (ABIN7538486)

Target

See all PRLHR Proteins
PRLHR (Prolactin Releasing Hormone Receptor (PRLHR))

Protein Type

Synthetic Nanodisc

Origin

  • 6
  • 2
Human

Source

  • 4
  • 2
  • 2
Mammalian Cells
  • Purpose

    Human PRLHR full length protein-synthetic nanodisc

    Characteristics

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    PRLHR (Prolactin Releasing Hormone Receptor (PRLHR))

    Alternative Name

    PRLHR

    Background

    PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH, MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008]

    Molecular Weight

    The human full length PRLHR protein has a MW of 41.1kDa

    UniProt

    P49683

    Pathways

    Feeding Behaviour
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