Selectin E/CD62e Protein (AA 22-556) (His tag)
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- Target See all Selectin E/CD62e (SELE) Proteins
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-556
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Origin
- Human
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Source
- Mammalian Cells
- Purification tag / Conjugate
- This Selectin E/CD62e protein is labelled with His tag.
- Purpose
- Recombinant human CD62E Protein with C-terminal 6xHis tag
- Specificity
- CD62E (Trp22-Pro556) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SELE Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- Alternative Name
- CD62E (SELE Products)
- Background
- The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 59.5 kDa after removal of the signal peptide. The apparent molecular mass of CD62E-His is 100-130 kDa due to glycosylation.
- UniProt
- P16581
- Pathways
- Thromboxane A2 Receptor Signaling
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