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TAAR1 Protein

This Synthetic Nanodisc TAAR1 protein is expressed in Mammalian Cells.
Catalog No. ABIN7538556

Quick Overview for TAAR1 Protein (ABIN7538556)

Target

See all TAAR1 Proteins
TAAR1 (Trace Amine Associated Receptor 1 (TAAR1))

Protein Type

Synthetic Nanodisc

Origin

  • 5
  • 2
Human

Source

  • 3
  • 2
  • 2
Mammalian Cells
  • Purpose

    Human TAAR1 full length protein-synthetic nanodisc

    Characteristics

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    TAAR1 (Trace Amine Associated Receptor 1 (TAAR1))

    Alternative Name

    TAAR1

    Background

    The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopamine, and tryptamine. While primarily functioning in neurologic systems, there is evidence that this gene is involved in blood cell and immunologic functions as well. This gene is thought to be intronless. [provided by RefSeq, Nov 2015]

    Molecular Weight

    The human full length TAAR1 protein has a MW of 39.1kDa

    UniProt

    Q96RJ0
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