TNFRSF8 Protein (AA 28-393) (His tag)
Quick Overview for TNFRSF8 Protein (AA 28-393) (His tag) (ABIN7852682)
Target
See all TNFRSF8 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 28-393
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Purification tag / Conjugate
- This TNFRSF8 protein is labelled with His tag.
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Purpose
- Recombinant Cynomolgus CD30 protein with C-terminal 10xHis tag
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Specificity
- CD30 (Asp28-Gly393) 10xHis tag
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
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Alternative Name
- CD30
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Background
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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Molecular Weight
- predicted molecular mass of 40.0 kDa after removal of the signal peptide.
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UniProt
- A0A2K5VW07
Target
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