KIF2B Protein (AA 1-673) (His tag)

Catalog No. ABIN7548739

This Recombinant KIF2B protein is produced in HEK-293 Cells.

Quick Overview for KIF2B Protein (AA 1-673) (His tag) (ABIN7548739)

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-673

Purification tag / Conjugate: This KIF2B protein is labelled with His tag.

Purpose: Predefined custom protein recombinant KIF2B Protein expressed in mammalian cells.

Sequence: MASQFCLPES PCLSPLKPLK PHFGDIQEGI YVAIQRSDKR IHLAVVTEIN RENYWVTVEW VEKAVKKGKK IDLETILLLN PALDSAEHPM PPPPLSPLAL APSSAIRDQR TATKWVAMIP QKNQTASGDS LDVRVPSKPC LMKQKKSPCL WEIQKLQEQR EKRRRLQQEI RARRALDVNT RNPNYEIMHM IEEYRRHLDS SKISVLEPPQ EHRICVCVRK RPLNQRETTL KDLDIITVPS DNVVMVHESK QKVDLTRYLQ NQTFCFDHAF DDKASNELVY QFTAQPLVES IFRKGMATCF AYGQTGSGKT YTMGGDFSGT AQDCSKGIYA LVAQDVFLLL RNSTYEKLDL KVYGTFFEIY GGKVYDLLNW KKKLQVLEDG NQQIQVVGLQ EKEVCCVEEV LNLVEIGNSC RTSRQTPVNA HSSRSHAVFQ IILKSGRIMH GKFSLVDLAG NERGADTTKA SRKRQLEGAE INKSLLALKE CILALGQNKP HTPFRASKLT LVLRDSFIGQ NSSTCMIATI SPGMTSCENT LNTLRYANRV KKLNVDVRPY HRGHYPIGHE APRMLKSHIG NSEMSLQRDE FIKIPYVQSE EQKEIEEVET LPTLLGKDTT ISGKGSSQWL ENIQERAGGV HHDIDFCIAR SLSILEQKID ALTEIQKKLK LLLADLHVKS KVE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Alternative Name: KIF2B

Background: Kinesin-like protein KIF2B,FUNCTION: Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity (PubMed:17538014). Plays a role in chromosome congression (PubMed:23891108). {ECO:0000269|PubMed:17538014, ECO:0000269|PubMed:23891108}.

Molecular Weight: 76.3 kDa

UniProt: Q8N4N8

AlphaFold: Q8N4N8

Pathways: Microtubule Dynamics