CCDC147 Protein (AA 1-872) (His tag)

Catalog No. ABIN7553360

This Recombinant CCDC147 protein is expressed in HEK-293 Cells.

Quick Overview for CCDC147 Protein (AA 1-872) (His tag) (ABIN7553360)

Target: CCDC147 (Coiled-Coil Domain Containing 147 (CCDC147))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-872

Purification tag / Conjugate: This CCDC147 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant CFAP58 Protein expressed in mammalian cells.

Sequence: MAEEKGGKQV LEESAFEEME RDFQGVLHEL SGDKSLEKFR IEYERLHAVM KKSYDNEKRL MAKCRELNAE IVVNSAKVAT ALKLSQDDQT TIASLKKEIE KAWKMVDSAY DKEQKAKETI LALKEEIVNL TKLVEQGSGL SMDQHSNIRD LLRFKEEVTK ERDQLLSEVV KLRESLAQTT EQQQETERSK EEAEHAISQF QQEIQQRQNE ASREFRKKEK LEKELKQIQA DMDSRQTEIK ALQQYVQKSK EELQKLEQQL KEQKILNERA AKELEQFQMR NAKLQQENEQ HSLVCEQLSQ ENQQKALELK AKEEEVHQMR LDIGKLNKIR EQIHKKLHHT EDQKAEVEQH KETLKNQIVG LEREVEASKK QAELDRKAMD ELLRERDILN KNMLKAVNAT QKQTDLVKLH EQAKRNLEGE IQNYKDEAQK QRKIIFHLEK ERDRYINQAS DLTQKVLMNM EDIKVRETQI FDYRKKIAES EIKLKQQQNL YEAVRSDRNL YSKNLVEAQD EITDMKRKLK IMIHQVDELK EDISAKESAL VKLHLEQQRI EKEKETLKAE LQKLRQQALE TKHFIEKQEA EERKLLRIIA EADGERLRQK KELDQVISER DILGSQLVRR NDELALLYEK IKIQQSVLNK GESQYNQRLE DMRILRLEIK KLRREKGILA RSMANVEELR QEFFHMQREL LKERTRCRAL EEELENPLNV HRWRKLEASD PNAYELIQKI HTLQKRLISK TEEVVEKELL LQEKEKLYME LKHVLARQPG PEAAEQLKLY RRTLHDKKQQ LKVLSSELNM YEVQSKEYKY EVEKLTNELQ NLKKKYLAQK RKEQLQKNKD TAPMDNTFLM VKPNGPGFTG GGFPLRSTKM TF Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CCDC147 (Coiled-Coil Domain Containing 147 (CCDC147))

Alternative Name: CFAP58

Background: Cilia- and flagella-associated protein 58 (Coiled-coil domain-containing protein 147),FUNCTION: Has an essential role in the assembly and organization of the sperm flagellar axoneme (PubMed:32791035). Required for the elongation of the primary cilium and sperm flagellar midpiece via modulation of the Notch signaling pathway (By similarity). {ECO:0000250|UniProtKB:B2RW38, ECO:0000269|PubMed:32791035}.

Molecular Weight: 103.4 kDa

UniProt: Q5T655

AlphaFold: Q5T655