IL16 Protein (AA 1-1332) (His tag)

Catalog No. ABIN7554157

This Recombinant IL16 protein is produced in HEK-293 Cells.

Quick Overview for IL16 Protein (AA 1-1332) (His tag) (ABIN7554157)

Target: IL16 (Interleukin 16 (IL16))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1332

Purification tag / Conjugate: This IL16 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant IL16 Protein expressed in mammalian cells.

Sequence: MESHSRAGKS RKSAKFRSIS RSLMLCNAKT SDDGSSPDEK YPDPFEISLA QGKEGIFHSS VQLADTSEAG PSSVPDLALA SEAAQLQAAG NDRGKTCRRI FFMKESSTAS SREKPGKLEA QSSNFLFPKA CHQRARSNST SVNPYCTREI DFPMTKKSAA PTDRQPYSLC SNRKSLSQQL DCPAGKAAGT SRPTRSLSTA QLVQPSGGLQ ASVISNIVLM KGQAKGLGFS IVGGKDSIYG PIGIYVKTIF AGGAAAADGR LQEGDEILEL NGESMAGLTH QDALQKFKQA KKGLLTLTVR TRLTAPPSLC SHLSPPLCRS LSSSTCITKD SSSFALESPS APISTAKPNY RIMVEVSLQK EAGVGLGIGL CSVPYFQCIS GIFVHTLSPG SVAHLDGRLR CGDEIVEISD SPVHCLTLNE VYTILSHCDP GPVPIIVSRH PDPQVSEQQL KEAVAQAVEN TKFGKERHQW SLEGVKRLES SWHGRPTLEK EREKNSAPPH RRAQKVMIRS SSDSSYMSGS PGGSPGSGSA EKPSSDVDIS THSPSLPLAR EPVVLSIASS RLPQESPPLP ESRDSHPPLR LKKSFEILVR KPMSSKPKPP PRKYFKSDSD PQKSLEEREN SSCSSGHTPP TCGQEARELL PLLLPQEDTA GRSPSASAGC PGPGIGPQTK SSTEGEPGWR RASPVTQTSP IKHPLLKRQA RMDYSFDTTA EDPWVRISDC IKNLFSPIMS ENHGHMPLQP NASLNEEEGT QGHPDGTPPK LDTANGTPKV YKSADSSTVK KGPPVAPKPA WFRQSLKGLR NRASDPRGLP DPALSTQPAP ASREHLGSHI RASSSSSSIR QRISSFETFG SSQLPDKGAQ RLSLQPSSGE AAKPLGKHEE GRFSGLLGRG AAPTLVPQQP EQVLSSGSPA ASEARDPGVS ESPPPGRQPN QKTLPPGPDP LLRLLSTQAE ESQGPVLKMP SQRARSFPLT RSQSCETKLL DEKTSKLYSI SSQVSSAVMK SLLCLPSSIS CAQTPCIPKE GASPTSSSNE DSAANGSAET SALDTGFSLN LSELREYTEG LTEAKEDDDG DHSSLQSGQS VISLLSSEEL KKLIEEVKVL DEATLKQLDG IHVTILHKEE GAGLGFSLAG GADLENKVIT VHRVFPNGLA SQEGTIQKGN EVLSINGKSL KGTTHHDALA ILRQAREPRQ AVIVTRKLTP EAMPDLNSST DSAASASAAS DVSVESTAEA TVCTVTLEKM SAGLGFSLEG GKGSLHGDKP LTINRIFKGA ASEQSETVQP GDEILQLGGT AMQGLTRFEA WNIIKALPDG PVTIVIRRKS LQSKETTAAG DS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: IL16 (Interleukin 16 (IL16))

Alternative Name: IL16

Background: Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)],FUNCTION: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4., FUNCTION: [Isoform 1]: May act as a scaffolding protein that anchors ion channels in the membrane., FUNCTION: Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Molecular Weight: 141.8 kDa

UniProt: Q14005

AlphaFold: Q14005