ASB4 Protein (AA 1-426) (His tag)

Catalog No. ABIN7556303

This Recombinant ASB4 protein is expressed in HEK-293 Cells.

Quick Overview for ASB4 Protein (AA 1-426) (His tag) (ABIN7556303)

Target: ASB4 (Ankyrin Repeat and SOCS Box Containing 4 (ASB4))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-426

Purification tag / Conjugate: This ASB4 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Asb4 Protein expressed in mammalian cells.

Sequence: MDGITAPISK AGAAKLVKKD FLEALKTNDF GKLKAILIER QIDVDTVFEV EDENMILASY KQGYWLPSYK LKSSWATGLH LSVLLGHVEC LMVLLDHNAT INCRPNGKTP LHVACEIANL ECVKILCDRG AKLNCYSLSG HTALHFCTTP SSILCAKQLV LRGANVNMKT NNQDEETPLH TAAHFGLSEL VAFYVENGAI VDSMNAHMET PLAIATYWAL RFKEQEYSRE HHLICRTLLD NNAEVNARDD DFKSPLHKAA WNCDHVLMHM MLEAGAEANL MDINGCAAIQ YVLKVTSVRP AAQPEICYQL LLNHGAARIY PPQFHKVIQA CHSCPKAIEV VVNAYEHIRW NIKWRRAIPD DDLEKHWDFY HSLFKVCCNT PRTLMHLSRC AIRKALHNRC HKAIPMLSLP LPLKKYLLLE PEGIIY Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ASB4 (Ankyrin Repeat and SOCS Box Containing 4 (ASB4))

Alternative Name: Asb4

Background: Ankyrin repeat and SOCS box protein 4 (ASB-4),FUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism. {ECO:0000269|PubMed:17636018}.

Molecular Weight: 48.1 kDa

UniProt: Q9WV71

AlphaFold: Q9WV71